Black Seed Oil

Black seed oil is a substance that is extracted from the seeds of Nigella sativa, a plant that is native to Egypt, the sub-continent and Asia. Black seed and black seed oil have long been used as herbal medicine for skin conditions, such as eczema, psoriasis, acne and dry skin, allergies, colds and more serious health conditions, such as asthma, arthritis, cancer and diabetes. 

Black seed, when taken by mouth in small quantities, such as a flavoring for foods, is LIKELY SAFE for most people. Black seed oil and black seed extract are POSSIBLY SAFE when medical amounts are used short-term. There isn't enough information to know if larger, medicinal quantities are safe. Black seed can cause allergic rashes when applied to the skin. Pregnancy and breast-feeding: Black seed seems to be safe in food amounts during pregnancy. But taking larger medicinal amounts is LIKELY UNSAFE. Black seed can slow down or stop the uterus from contracting. Diabetes: Black seed might lower blood sugar levels in some people. Watch for signs of low blood sugar (hypoglycemia) and monitor your blood sugar carefully if you have diabetes and use black seed.

They come from Nigella sativa, a small plant with pale purple, blue, or white flowers that grows in Eastern Europe, Western Asia, and the Middle East. People have used the tiny black seeds of N. sativa fruits as a natural remedy for thousands of years. The seeds can also flavor curries, pickles, and bread in a similar way to cumin or oregano. Black seed oil containsTrusted Source thymoquinone, which is an antioxidant and anti-inflammatory compound that may also have tumor-reducing properties. People can ingest black seed oil in the form of capsules or apply it topically to benefit the skin. It is also possible to add the oil to massage oils, shampoos, homemade skincare products, and fragrances.

The medicinal use of black cumin seeds in various traditional herbal systems is known for a wide range of ailments which include different airway disorders, for pain such as chronic headache and back pain, diabetes, paralysis, infection, inflammation, hypertension, and digestive tract related problems administered in different kind of preparations. It has also been used topically where it is applied directly to the blisters, nasal abscesses, orchitis, eczema, and swollen joints [33]. Keeping in view of the numerous traditional medicinal uses of N. sativa seeds and its active component, thymoquinone, this valuable herb can be explored as an effective folk medicine with multiple pharmacological actions.

Black Seed Oil

Infertility is the incapability of a copulate to attain offspring after 12 months of intercourse without contraception. It is more prevalent among men than women [142]. Sperm dysfunction is the main problem related with men infertility which accounts 60% of all reasons. The structure, function, motility, and survival of sperm are deleteriously affected by oxidative stress that prominently leads to infertility. Hence, increasing spermatozoa counts, functionality, and sperm quality using antioxidants can improve fertility status [143, 144]. Evidence proves that some herbal medicines can reduce negative effects of oxidative stress by salvaging free radicals [145]. Among the various traditional plants, N. sativa was found to exhibit remarkable antioxidant effect [146].

Thymoquinone obtained from seeds of N. sativa revealed broader spectrum activities against multiple strains of gram-positive and gram-negative bacteria, including Bacillus, Listeria, Enterococcus, Micrococcus, Staphylococcus, Pseudomonas, Escherichia, Salmonella, Serovar, and Vibrio parahaemolyticus in addition to inhibiting bacterial biofilm formation [105]. The methyl alcoholic extract of the seed also displayed a larger inhibition zone on gram-positive (S. pyogenes) as compared to gram-negative bacteria (P. aeruginosa, K. pneumoniae, and P. vulgaris) [106]. For different isolates of methicillin-resistant S. aureus, various concentrations of (100%, 80%, 50%, 40%, 30%, and 20%) N. sativa oils displayed an expressively higher zone of inhibitions against all the tested bacterial strains [107]. Thymoquinone also revealed a significant bactericidal activity against gram-positive cocci with MICs ranging from 8 to 32 μg/mL and proved the minimum biofilm inhibition concentration at 22 and 60 μg/mL for S. aureus and S. epidermidis, respectively [108]. Moreover, black seed (2 g/day) owed clinically valuable anti-H. pylori effect comparable to triple therapy [109] and this can provide a scientific basis for the exploration of potential uses of this valued seed for the treatment of H. pylori-induced gastric ulcers.